Professor Luke O'Neill

BSc (Biochemistry, TCD), PhD in Pharmacology (1988) from University of London, FTCD

THI Role

TCD nominee

Current Job

Professor Luke O'Neill was appointed to the Chair of Biochemistry at Trinity College Dublin in 2008, where he leads the Inflammation Research Group. He is also Academic Director of the Trinity Biomedical Sciences Institute.

Career History

He has a PhD in Pharmacology from the University of London and was an MRC Post Doctoral Fellow at the Strangeways Laboratory in Cambridge. He has won numerous awards for his research, notably the Royal Irish Academy Medal for Biochemistry, The Irish Society for Immunology medal, the Royal Dublin Society/ Irish Times Boyle medal for Scientific Excellence and the Science Foundation Ireland Researcher of the Year Award 2009. He was elected a member of EMBO in 2005. He is a co-founder and director of Opsona Therapeutics. In 2000, he was appointed Director of the Biotechnology Institute. In 2002 he was appointed Science Foundation Ireland Research Professor, and I currently hold the Chair of Biochemistry at Trinity College Dublin, where I was also Head of the School of Biochemistry and Immunology from 2004-2008.


His research is in the area of the molecular basis to inflammatory diseases, with a particular interest in pro-inflammatory cytokines and Toll-like receptors. He has published over 200 papers and reviews on his research, in journals such as Nature, Science, Cell, Nature Immunology, Nature Medicine, Nature Genetics and PNAS. He is on the editorial boards of 6 journals, including the Journal of Biological Chemistry and Trends in Immunology. He is also on the Board of Reviewing Editors for Science, covering Innate Immunity.

Advisory /Committees

In 2008 he was appointed Chair of the Immunity and Infection panel of the European Research Council.

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